Best Dog Melatonin for Medium Dogs in 2025
Updated on June 2025
#1
Recommended
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- Melatonin for larger dogs: Each chewable tablet contains 6 mg of melatonin, recommended for dogs over 30 lbs, with 90 beef-flavored tablets per bottle.
- Promotes calmness: Helps dogs manage anxiety during stressful situations such as thunderstorms and fireworks.
- Supports sleep cycle: Aids in regulating sleep patterns for a more balanced and peaceful routine.
- Boosts health: Nutritional formula enhances resilience against health challenges and supports overall vitality in dogs.
- Nutrient-rich formula: Provides natural support for skin and coat health while promoting tranquility.
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- Melatonin for larger dogs: Each chewable tablet contains 6 mg of melatonin, recommended for dogs over 30 lbs, with 90 beef-flavored tablets per bottle.
- Promotes calmness: Helps dogs manage anxiety during stressful situations such as thunderstorms and fireworks.
- Supports sleep cycle: Aids in regulating sleep patterns for a more balanced and peaceful routine.
- Boosts health: Nutritional formula enhances resilience against health challenges and supports overall vitality in dogs.
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#2
Value for Money
15% Off
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- Helps alleviate anxiety in pets during stressful situations such as fireworks, storms, vet visits, and car rides.
- Supports overall calmness, reduces hyperactive behavior, and minimizes aggressive tendencies in dogs.
- Suitable for all dog sizes, providing effective anxiety relief for puppies and senior dogs alike.
- Contains a natural formula with hemp oil, ensuring safety and effectiveness for puppies.
- Soft and tasty chews offer a preferred alternative to traditional pills or tablets for calming effects.
- Recommended for daily use to maintain a consistent calming effect for your pet.
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- Helps alleviate anxiety in pets during stressful situations such as fireworks, storms, vet visits, and car rides.
- Supports overall calmness, reduces hyperactive behavior, and minimizes aggressive tendencies in dogs.
- Suitable for all dog sizes, providing effective anxiety relief for puppies and senior dogs alike.
- Contains a natural formula with hemp oil, ensuring safety and effectiveness for puppies.
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#3
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- Calming soft chews for dogs to support nervous system function during stressful situations like separation or storms.
- Provides anxiety support for dogs, reducing stress and tension effectively.
- Contains melatonin, ginger, L-Tryptophan, and thiamin to help alleviate anxiety in dogs over 12 weeks old.
- Soft chews are palatable and packaged in a re-sealable jar to maintain freshness.
- Produced by NaturVet, a trusted brand in pet supplements since 1994, ensuring quality and compliance with safety standards.
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- Calming soft chews for dogs to support nervous system function during stressful situations like separation or storms.
- Provides anxiety support for dogs, reducing stress and tension effectively.
- Contains melatonin, ginger, L-Tryptophan, and thiamin to help alleviate anxiety in dogs over 12 weeks old.
- Soft chews are palatable and packaged in a re-sealable jar to maintain freshness.
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#4
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- Contains ingredients like hemp oil, valerian root, and chamomile for a natural approach to alleviating anxiety in dogs.
- Helps to reduce stress responses in dogs, making it effective for calming during events such as thunderstorms, car rides, vet visits, or separation anxiety.
- Aids in managing aggressive or hyperactive behavior, promoting a calmer environment for dogs in stressful situations.
- Developed by veterinarians and produced in an FDA-registered facility in the USA, ensuring high-quality and safety standards.
- Suitable for all dogs regardless of age or size, from puppies to senior dogs, providing a sleeping aid that meets diverse needs.
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- Contains ingredients like hemp oil, valerian root, and chamomile for a natural approach to alleviating anxiety in dogs.
- Helps to reduce stress responses in dogs, making it effective for calming during events such as thunderstorms, car rides, vet visits, or separation anxiety.
- Aids in managing aggressive or hyperactive behavior, promoting a calmer environment for dogs in stressful situations.
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#5
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- Contains melatonin to promote a calming response in dogs, helping them relax during stressful situations like loud noises or thunderstorms.
- Regulates biological clock for better sleep quality, aiding dogs in achieving a natural sleep state and reducing nighttime anxiety.
- Suitable for various stressful scenarios, including storms, fireworks, travel, vet visits, and separation anxiety, providing effective calming support.
- Made with safe, healthy ingredients like organic chamomile, L-tryptophan, valerian root, and vitamin B1, while appealing to dogs with a chicken flavor.
- Addresses multiple stress-related issues, helping pets cope with new environments and excessive excitement, ensuring a comprehensive calming effect.
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- Contains melatonin to promote a calming response in dogs, helping them relax during stressful situations like loud noises or thunderstorms.
- Regulates biological clock for better sleep quality, aiding dogs in achieving a natural sleep state and reducing nighttime anxiety.
- Suitable for various stressful scenarios, including storms, fireworks, travel, vet visits, and separation anxiety, providing effective calming support.
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#6
30% Off
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- Formulated by veterinarians and manufactured in the USA, Mighty Calm is designed to help your dog achieve a relaxed state.
- Contains melatonin, chamomile, and L-tryptophan, targeting stress factors such as separation anxiety and loud noises.
- These soft chews are specifically made for promoting peaceful behavior using a blend of calming ingredients.
- Available in a bacon flavor that appeals to dogs, making it easy to give your pet the supplement they need.
- Mighty Paw is a dedicated company based in Rochester, NY, committed to providing high-quality products for dogs.
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- Formulated by veterinarians and manufactured in the USA, Mighty Calm is designed to help your dog achieve a relaxed state.
- Contains melatonin, chamomile, and L-tryptophan, targeting stress factors such as separation anxiety and loud noises.
- These soft chews are specifically made for promoting peaceful behavior using a blend of calming ingredients.
- Available in a bacon flavor that appeals to dogs, making it easy to give your pet the supplement they need.
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#7
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- Supports everyday stress relief for dogs, crafted to reduce nervous and hyperactive behavior.
- Helps ease anxiety during separation, fireworks, travel, or thunderstorms for dogs of any size or breed.
- Contains a blend of melatonin, Chamomile, Valerian Root, Ashwagandha, and L-Theanine for promoting relaxation.
- Incorporates NutrientBoost technology to enhance gut health and immune support with essential nutrients.
- Features a bacon flavor that dogs enjoy, combining calming ingredients for effective stress relief.
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- Supports everyday stress relief for dogs, crafted to reduce nervous and hyperactive behavior.
- Helps ease anxiety during separation, fireworks, travel, or thunderstorms for dogs of any size or breed.
- Contains a blend of melatonin, Chamomile, Valerian Root, Ashwagandha, and L-Theanine for promoting relaxation.
- Incorporates NutrientBoost technology to enhance gut health and immune support with essential nutrients.
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#8
17% Off
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- Day & Night Calming Support helps dogs manage stress during various situations, with a daytime formula for relaxation and a nighttime formula promoting natural sleep cycles.
- Contains a blend of natural ingredients like Hemp Seed Oil, Valerian Root, and Ashwagandha, designed to support well-being and focus, making it suitable for training and behavioral management.
- Features Hemp Seed Oil and Celery Seed Powder for overall wellness, supporting skin and joint health, while the nighttime melatonin formula helps maintain a natural sleep cycle for restorative rest.
- Suitable for all dog breeds and sizes over 12 weeks, with easy-to-administer liquid form that allows for weight-based dosing for effective support.
- Precise dropper for easy dosing based on weight, with the option to mix with food or water; available in flavors that appeal to picky eaters.
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- Day & Night Calming Support helps dogs manage stress during various situations, with a daytime formula for relaxation and a nighttime formula promoting natural sleep cycles.
- Contains a blend of natural ingredients like Hemp Seed Oil, Valerian Root, and Ashwagandha, designed to support well-being and focus, making it suitable for training and behavioral management.
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#9
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- Vet-recommended chews designed to manage anxiety in dogs.
- Effective for addressing separation anxiety, excess energy, and travel-related stress.
- Natural alternative to dog sleeping pills, featuring melatonin for improved sleep.
- Hemp-based chews that provide anxiety and stress relief, made with all-natural ingredients.
- Real chicken flavor in freeze-dried treats, without fillers, suitable for travel or daily use.
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- Vet-recommended chews designed to manage anxiety in dogs.
- Effective for addressing separation anxiety, excess energy, and travel-related stress.
- Natural alternative to dog sleeping pills, featuring melatonin for improved sleep.
- Hemp-based chews that provide anxiety and stress relief, made with all-natural ingredients.
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#10
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- Liquid melatonin for dogs available in an easy-to-use dropper format for stress relief during thunder and car rides.
- Melatonin aids in regulating sleep cycles, providing support for dogs experiencing insomnia or sleep disruptions.
- Contains L-Theanine to help reduce anxiety and stress in dogs, ideal during stressful situations such as vet visits or separation.
- Supports immune health and overall vitality for all dog breeds, contributing to daily well-being.
- Promotes healthy skin and coat by balancing adrenal secretion and supporting hair growth.
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- Liquid melatonin for dogs available in an easy-to-use dropper format for stress relief during thunder and car rides.
- Melatonin aids in regulating sleep cycles, providing support for dogs experiencing insomnia or sleep disruptions.
- Contains L-Theanine to help reduce anxiety and stress in dogs, ideal during stressful situations such as vet visits or separation.
- Supports immune health and overall vitality for all dog breeds, contributing to daily well-being.
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