Best Cold & Flu Medicine in 2025
Updated on July 2025
#1
Recommended
25% Off
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- Combo pack includes Mucinex Fast-Max Day and Night Cold & Flu liquid gels for relief of cold and flu symptoms.
- Contains Acetaminophen for reducing fever and alleviating sore throat, headache, and body aches.
- Dextromethorphan HBr effectively suppresses cough.
- Daytime gel includes Guaifenesin, aiding in loosening mucus and relieving chest congestion.
- Phenylephrine HCl helps relieve stuffy nose and sinus pressure.
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- Combo pack includes Mucinex Fast-Max Day and Night Cold & Flu liquid gels for relief of cold and flu symptoms.
- Contains Acetaminophen for reducing fever and alleviating sore throat, headache, and body aches.
- Dextromethorphan HBr effectively suppresses cough.
- Daytime gel includes Guaifenesin, aiding in loosening mucus and relieving chest congestion.
- Phenylephrine HCl helps relieve stuffy nose and sinus pressure.
#2
Value for Money
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- ACTIVE INGREDIENTS: Contains key components for effective treatment of cold and flu symptoms.
- NON-DROWSY RELIEF: Alleviates common cold and flu symptoms such as headaches, fever, sore throat, cough, and minor aches without drowsiness.
- NIGHTTIME RELIEF: Targets nighttime cold and flu symptoms including fever, sore throat, and nasal congestion to promote restful sleep.
- PAIN AND FEVER MANAGEMENT: Both formulations include acetaminophen to alleviate pain, fever, and sore throat.
- COLD AND FLU EXPLANATION: Aids in addressing respiratory illnesses caused by viruses like influenza and the common cold.
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- ACTIVE INGREDIENTS: Contains key components for effective treatment of cold and flu symptoms.
- NON-DROWSY RELIEF: Alleviates common cold and flu symptoms such as headaches, fever, sore throat, cough, and minor aches without drowsiness.
- NIGHTTIME RELIEF: Targets nighttime cold and flu symptoms including fever, sore throat, and nasal congestion to promote restful sleep.
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#3
16% Off
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- Combo pack includes 24 caplets: 16 Daytime and 8 Nighttime for cold and flu relief.
- Daytime caplets address fever, cough, sore throat, and nasal congestion.
- Nighttime caplets provide relief from runny nose, sneezing, and sinus pressure while promoting rest.
- Each caplet contains acetaminophen for pain and fever, phenylephrine as a decongestant, and dextromethorphan as a cough suppressant.
- Daytime caplets feature guaifenesin to loosen phlegm; Nighttime caplets include an antihistamine for added relief.
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- Combo pack includes 24 caplets: 16 Daytime and 8 Nighttime for cold and flu relief.
- Daytime caplets address fever, cough, sore throat, and nasal congestion.
- Nighttime caplets provide relief from runny nose, sneezing, and sinus pressure while promoting rest.
- Each caplet contains acetaminophen for pain and fever, phenylephrine as a decongestant, and dextromethorphan as a cough suppressant.
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#4
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- Active ingredients include 650 mg Acetaminophen, 30 mg Dextromethorphan HBr, and 12.5 mg Doxylamine succinate.
- Provides relief from cold and flu symptoms such as aches, fever, cough, sneezing, and runny nose.
- Designed to alleviate nighttime cold and flu symptoms for better rest.
- Functions as a pain reliever, fever reducer, cough suppressant, and antihistamine.
- Gluten-free formulation containing 10% alcohol.
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- Active ingredients include 650 mg Acetaminophen, 30 mg Dextromethorphan HBr, and 12.5 mg Doxylamine succinate.
- Provides relief from cold and flu symptoms such as aches, fever, cough, sneezing, and runny nose.
- Designed to alleviate nighttime cold and flu symptoms for better rest.
- Functions as a pain reliever, fever reducer, cough suppressant, and antihistamine.
- Gluten-free formulation containing 10% alcohol.
#5
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- Contains comparison of active ingredients with Vicks DayQuil and NyQuil Severe
- Daytime formula includes acetaminophen for pain relief, dextromethorphan for cough suppression, guaifenesin for expectoration, and phenylephrine for nasal decongestion
- Nighttime formula includes acetaminophen for pain relief, dextromethorphan for cough suppression, doxylamine as an antihistamine, and phenylephrine for nasal decongestion
- Provides relief for cold and flu symptoms both during the day and at night
- Offers maximum strength support for severe cold and flu symptoms
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- Contains comparison of active ingredients with Vicks DayQuil and NyQuil Severe
- Daytime formula includes acetaminophen for pain relief, dextromethorphan for cough suppression, guaifenesin for expectoration, and phenylephrine for nasal decongestion
- Nighttime formula includes acetaminophen for pain relief, dextromethorphan for cough suppression, doxylamine as an antihistamine, and phenylephrine for nasal decongestion
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#6
16% Off
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- Contains acetaminophen for pain relief and fever reduction, dextromethorphan HBr as a cough suppressant, and phenylephrine HCl for nasal decongestion.
- Relieves multiple symptoms including headache, fever, sore throat, nasal congestion, and cough associated with colds and flu.
- Acts as a cough suppressant to alleviate coughing due to throat and bronchial irritation during cold and flu season.
- Helps relieve nasal congestion, a common symptom during cold and flu seasons.
- This product is part of an Amazon Brand.
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- Contains acetaminophen for pain relief and fever reduction, dextromethorphan HBr as a cough suppressant, and phenylephrine HCl for nasal decongestion.
- Relieves multiple symptoms including headache, fever, sore throat, nasal congestion, and cough associated with colds and flu.
- Acts as a cough suppressant to alleviate coughing due to throat and bronchial irritation during cold and flu season.
- Helps relieve nasal congestion, a common symptom during cold and flu seasons.
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#7
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- Non-drowsy daytime relief with DayQuil SEVERE and fast-acting nighttime relief with NyQuil SEVERE.
- Temporarily alleviates common cold and flu symptoms effectively.
- Quick onset of relief with just one dose for cold and flu symptoms.
- Targets intense cold and flu symptoms for uninterrupted daily activities.
- Vicks, with over 125 years of trust, is the leading OTC brand for cough and cold relief.
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- Non-drowsy daytime relief with DayQuil SEVERE and fast-acting nighttime relief with NyQuil SEVERE.
- Temporarily alleviates common cold and flu symptoms effectively.
- Quick onset of relief with just one dose for cold and flu symptoms.
- Targets intense cold and flu symptoms for uninterrupted daily activities.
- Vicks, with over 125 years of trust, is the leading OTC brand for cough and cold relief.
#8
24% Off
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- Contains active ingredients comparable to Vicks DayQuil and NyQuil Severe VapoCOOL for cold and flu symptom relief day and night.
- Daytime formula alleviates aches, fever, nasal congestion, sinus pressure, cough, and chest congestion; Nighttime formula targets aches, fever, nasal congestion, sneezing, runny nose, and cough.
- Combination pack offers continuous, maximum strength relief for severe cold and flu symptoms around the clock.
- Coated caplets include a pain reliever, fever reducer, cough suppressant, nasal decongestant, and an antihistamine (nighttime) / expectorant (daytime).
- Designed for maximum effectiveness in relieving common cold and flu symptoms throughout the day and night.
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- Contains active ingredients comparable to Vicks DayQuil and NyQuil Severe VapoCOOL for cold and flu symptom relief day and night.
- Daytime formula alleviates aches, fever, nasal congestion, sinus pressure, cough, and chest congestion; Nighttime formula targets aches, fever, nasal congestion, sneezing, runny nose, and cough.
- Combination pack offers continuous, maximum strength relief for severe cold and flu symptoms around the clock.
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#9
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- Active ingredients include acetaminophen, dextromethorphan HBr, guaifenesin, and phenylephrine HCl; comparable to Vicks DayQuil Severe Cold and Flu.
- Provides temporary relief from symptoms of cold and flu such as headache, fever, sore throat, body aches, nasal congestion, and cough.
- Non-alcoholic formula effectively reduces pain and fever associated with cold and flu symptoms.
- Offers non-drowsy relief from nasal and sinus congestion and pressure.
- Helps to suppress cough and loosen mucus for easier expulsion, improving the productivity of coughs.
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- Active ingredients include acetaminophen, dextromethorphan HBr, guaifenesin, and phenylephrine HCl; comparable to Vicks DayQuil Severe Cold and Flu.
- Provides temporary relief from symptoms of cold and flu such as headache, fever, sore throat, body aches, nasal congestion, and cough.
- Non-alcoholic formula effectively reduces pain and fever associated with cold and flu symptoms.
- Offers non-drowsy relief from nasal and sinus congestion and pressure.
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#10
28% Off
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- Contains 24 caplets per pack, designed for effective relief from flu and cold symptoms.
- Addresses fever, headaches, sore throats, nasal congestion, and coughs, while helping to loosen mucus.
- Each caplet includes 325 mg of acetaminophen for pain and fever relief, combined with 10 mg of dextromethorphan to suppress coughs.
- Incorporates 5 mg of phenylephrine as a nasal decongestant and 200 mg of guaifenesin to aid in mucus clearance and enhance cough productivity.
- Recommended for adults and children aged 12 and older, offering comprehensive relief from multiple symptoms.
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- Contains 24 caplets per pack, designed for effective relief from flu and cold symptoms.
- Addresses fever, headaches, sore throats, nasal congestion, and coughs, while helping to loosen mucus.
- Each caplet includes 325 mg of acetaminophen for pain and fever relief, combined with 10 mg of dextromethorphan to suppress coughs.
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