Best Ergonomic Mouse in 2025

Updated on June 2025
#1
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  • Designed for small to medium right hands, the Logitech Lift Vertical Ergonomic Mouse supports a natural grip.
  • Textured grip and thumb rest enhance comfort during extended use.
  • Vertical shape promotes better wrist posture and extended comfort for productivity.
  • Customizable buttons and SmartWheel allow for seamless scrolling and quiet operation.
  • Ergo-certified design meets standards established by leading ergonomists.
  • Connect via Bluetooth Low Energy or Logi Bolt USB, compatible with multiple OS, with up to 2 years battery life.
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  • Designed for small to medium right hands, the Logitech Lift Vertical Ergonomic Mouse supports a natural grip.
  • Textured grip and thumb rest enhance comfort during extended use.
  • Vertical shape promotes better wrist posture and extended comfort for productivity.
  • Customizable buttons and SmartWheel allow for seamless scrolling and quiet operation.
  • Ergo-certified design meets standards established by leading ergonomists.
  • Connect via Bluetooth Low Energy or Logi Bolt USB, compatible with multiple OS, with up to 2 years battery life.
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#2
Value for Money
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  • Ergonomic design promotes natural wrist and arm positions, reducing strain during use.
  • High DPI optical tracking technology offers enhanced sensitivity for precise movement across various surfaces.
  • Convenient next/previous buttons enhance browsing efficiency for internet users and gamers.
  • Automatic power-saving mode activates after 8 minutes of inactivity, easily reactivated with a button press.
  • Includes Anker Wireless Vertical Ergonomic Optical Mouse, USB receiver, and instruction manual; batteries not included.
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  • Ergonomic design promotes natural wrist and arm positions, reducing strain during use.
  • High DPI optical tracking technology offers enhanced sensitivity for precise movement across various surfaces.
  • Convenient next/previous buttons enhance browsing efficiency for internet users and gamers.
  • Automatic power-saving mode activates after 8 minutes of inactivity, easily reactivated with a button press.
  • Includes Anker Wireless Vertical Ergonomic Optical Mouse, USB receiver, and instruction manual; batteries not included.
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#3
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  • Connects seamlessly to three devices using Bluetooth (5.0/3.0) and 2.4GHz USB modes.
  • Features 6 adjustable DPI settings (800-4800) for versatile usage across different surfaces.
  • Operates quietly for distraction-free use in quiet settings like libraries, with near-silent left and right clicks.
  • Ergonomic design minimizes wrist pressure by encouraging a near-vertical hand position; designed for right-handed users.
  • Wide compatibility with Windows, Mac, Chrome, and Linux; has a low battery warning system.
  • Includes a 36-month warranty with access to professional customer service.
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  • Connects seamlessly to three devices using Bluetooth (5.0/3.0) and 2.4GHz USB modes.
  • Features 6 adjustable DPI settings (800-4800) for versatile usage across different surfaces.
  • Operates quietly for distraction-free use in quiet settings like libraries, with near-silent left and right clicks.
  • Ergonomic design minimizes wrist pressure by encouraging a near-vertical hand position; designed for right-handed users.
  • Wide compatibility with Windows, Mac, Chrome, and Linux; has a low battery warning system.
  • Includes a 36-month warranty with access to professional customer service.
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#4
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  • Ergonomic design with an extended wrist rest for reduced forearm and wrist fatigue.
  • Connects wirelessly to up to 3 devices via dual Bluetooth 5.0 and 2.4G USB; compatible with various operating systems including Windows, Mac, and Android.
  • Features a rechargeable 500mAh Li-Ion battery with Type-C charging capability.
  • Adjustable DPI settings (1000/1600/2400) for precise tracking; includes back and forward navigation buttons, though not programmable for Mac.
  • Whisper-quiet clicking design ideal for quiet environments like offices and libraries.
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  • Ergonomic design with an extended wrist rest for reduced forearm and wrist fatigue.
  • Connects wirelessly to up to 3 devices via dual Bluetooth 5.0 and 2.4G USB; compatible with various operating systems including Windows, Mac, and Android.
  • Features a rechargeable 500mAh Li-Ion battery with Type-C charging capability.
  • Adjustable DPI settings (1000/1600/2400) for precise tracking; includes back and forward navigation buttons, though not programmable for Mac.
  • Whisper-quiet clicking design ideal for quiet environments like offices and libraries.
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#5
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  • Sculpted design reduces hand movement and supports precise thumb control for extended comfort.
  • Developed with ergonomists to decrease forearm strain and enhance posture for prolonged use.
  • Features three customizable buttons and adjustable cursor speed via Logi Options+ App for efficient control.
  • Cursor movement is achievable without moving the hand, ideal for compact setups and various surfaces.
  • Compatible with Bluetooth and Logi Bolt USB receiver, offering long-lasting battery life of up to 18 months.
  • Made from recycled plastic to support sustainability efforts.
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  • Sculpted design reduces hand movement and supports precise thumb control for extended comfort.
  • Developed with ergonomists to decrease forearm strain and enhance posture for prolonged use.
  • Features three customizable buttons and adjustable cursor speed via Logi Options+ App for efficient control.
  • Cursor movement is achievable without moving the hand, ideal for compact setups and various surfaces.
  • Compatible with Bluetooth and Logi Bolt USB receiver, offering long-lasting battery life of up to 18 months.
  • Made from recycled plastic to support sustainability efforts.
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#6
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  • Designed for medium to large right hands for optimal comfort.
  • Natural handshake position minimizes muscular effort by 10% compared to traditional mice.
  • Unique 57° angle promotes better wrist alignment while providing a comfortable thumb rest.
  • High-precision 4000 DPI sensor decreases hand movement by 4x, with an adjustable cursor speed switch for quick DPI adjustments.
  • Ergonomic shape with a textured rubber surface designed for a secure grip and comfort.
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  • Designed for medium to large right hands for optimal comfort.
  • Natural handshake position minimizes muscular effort by 10% compared to traditional mice.
  • Unique 57° angle promotes better wrist alignment while providing a comfortable thumb rest.
  • High-precision 4000 DPI sensor decreases hand movement by 4x, with an adjustable cursor speed switch for quick DPI adjustments.
  • Ergonomic shape with a textured rubber surface designed for a secure grip and comfort.
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#7
21% Off
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  • Ergonomic design that supports a natural hand position for comfort during extended use.
  • Accurate cursor control with smooth thumb operation, adjustable speed via Logitech Options software.
  • Ideal for compact spaces as the stationary trackball allows for efficient use on busy desks.
  • Dual connectivity options via Bluetooth or USB receiver, with a reliable range of up to 33 ft (10m).
  • Constructed with post-consumer recycled plastic and responsibly packaged using FSC-certified materials.
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  • Ergonomic design that supports a natural hand position for comfort during extended use.
  • Accurate cursor control with smooth thumb operation, adjustable speed via Logitech Options software.
  • Ideal for compact spaces as the stationary trackball allows for efficient use on busy desks.
  • Dual connectivity options via Bluetooth or USB receiver, with a reliable range of up to 33 ft (10m).
  • Constructed with post-consumer recycled plastic and responsibly packaged using FSC-certified materials.
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#8
11% Off
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  • Ergonomic Design: The vertical structure promotes a natural wrist posture, reducing fatigue and discomfort during extended use, and alleviating shoulder and neck pressure.
  • Rechargeable Battery: A built-in 600mAh battery charges fully in 1.5 hours, offering up to 2 months of use. Features a Type-C charging interface and power-saving mode after 8 minutes of inactivity.
  • Stable Wireless Connectivity: Utilizes 2.4 GHz technology for reliable performance within a 10m range, supporting a plug-and-play setup with no additional drivers required.
  • Quiet Operation: Equipped with silent-click technology to minimize noise, making it suitable for use in quiet environments like libraries and hospitals, enhancing productivity without disturbing others.
  • Adjustable DPI: Features 5 DPI settings (800 to 4800) for precise tracking on various surfaces, accommodating different office tasks and user preferences.
  • Wide Compatibility: Designed for carpal tunnel support, this USB-A mouse works with desktops and laptops but is not compatible with USB-C devices.
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  • Ergonomic Design: The vertical structure promotes a natural wrist posture, reducing fatigue and discomfort during extended use, and alleviating shoulder and neck pressure.
  • Rechargeable Battery: A built-in 600mAh battery charges fully in 1.5 hours, offering up to 2 months of use. Features a Type-C charging interface and power-saving mode after 8 minutes of inactivity.
  • Stable Wireless Connectivity: Utilizes 2.4 GHz technology for reliable performance within a 10m range, supporting a plug-and-play setup with no additional drivers required.
  • Quiet Operation: Equipped with silent-click technology to minimize noise, making it suitable for use in quiet environments like libraries and hospitals, enhancing productivity without disturbing others.
  • Adjustable DPI: Features 5 DPI settings (800 to 4800) for precise tracking on various surfaces, accommodating different office tasks and user preferences.
  • Wide Compatibility: Designed for carpal tunnel support, this USB-A mouse works with desktops and laptops but is not compatible with USB-C devices.
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#9
10% Off
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  • Compact dimensions of 4.09" x 2.68" x 1.49" enhance portability for travel use, compatible with USB-A port devices only.
  • Ergonomically contoured shape with rubber side grips ensures comfort and support for prolonged use.
  • 5-level adjustable DPI settings (800-2600) enable precise tracking on various surfaces, excluding glass.
  • Designed for up to 24 months of battery life with power-saving features and an on/off switch.
  • Easy setup with a plug-and-play USB-A mini-receiver compatible with multiple operating systems.
  • Note: AAA batteries not included; USB receiver stored within the mouse.
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  • Compact dimensions of 4.09" x 2.68" x 1.49" enhance portability for travel use, compatible with USB-A port devices only.
  • Ergonomically contoured shape with rubber side grips ensures comfort and support for prolonged use.
  • 5-level adjustable DPI settings (800-2600) enable precise tracking on various surfaces, excluding glass.
  • Designed for up to 24 months of battery life with power-saving features and an on/off switch.
  • Easy setup with a plug-and-play USB-A mini-receiver compatible with multiple operating systems.
  • Note: AAA batteries not included; USB receiver stored within the mouse.
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#10
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  • Wireless connection options include Bluetooth (5.2/3.0) and 2.4GHz USB for versatile device pairing.
  • Connect to two devices simultaneously, with seamless switching between Bluetooth and USB connections at the press of a button.
  • Ergonomic vertical design promotes a natural handshake position to minimize wrist strain, featuring adjustable DPI settings for precision tracking.
  • Quiet operation with six silent buttons for undisturbed use in shared environments; includes back and forward buttons for efficient browsing (not compatible with Mac OS).
  • Rechargeable battery offers 1-3 months of use per charge via Type-C, with built-in power-saving mode that activates after 10 minutes of inactivity.
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  • Wireless connection options include Bluetooth (5.2/3.0) and 2.4GHz USB for versatile device pairing.
  • Connect to two devices simultaneously, with seamless switching between Bluetooth and USB connections at the press of a button.
  • Ergonomic vertical design promotes a natural handshake position to minimize wrist strain, featuring adjustable DPI settings for precision tracking.
  • Quiet operation with six silent buttons for undisturbed use in shared environments; includes back and forward buttons for efficient browsing (not compatible with Mac OS).
  • Rechargeable battery offers 1-3 months of use per charge via Type-C, with built-in power-saving mode that activates after 10 minutes of inactivity.
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